(2S)-2-(1H-tetrazol-1-yl)propanoic acid(SALTDATA
(2S)-2-(1H-Tetrazol-1-yl)propanoic acid
CAS: 1212174-51-0
Molecular Formula: C4H6N4O2
(2S)-2-(1H-tetrazol-1-yl)propanoic acid(SALTDATA - Names and Identifiers
(2S)-2-(1H-tetrazol-1-yl)propanoic acid(SALTDATA - Physico-chemical Properties
| Molecular Formula | C4H6N4O2 |
| Molar Mass | 142.12 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD11868184 |
(2S)-2-(1H-tetrazol-1-yl)propanoic acid(SALTDATA - Risk and Safety
| Hazard Class | IRRITANT |
(2S)-2-(1H-tetrazol-1-yl)propanoic acid(SALTDATA - Introduction
(2S)-2-(1H-tetrazol-1-yl) propionic acid is an organic compound with the chemical formula C5H7N5O2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
(2S)-2-(1H-tetrazol-1-yl) propionic acid is a colorless crystalline solid, soluble in water and some organic solvents. It is a chiral compound possessing two stereoisomers:(2S)-form and (2R)-form.
Use:
(2S)-2-(1H-tetrazol-1-yl) propionic acid is commonly used in the field of pharmaceutical chemistry as a synthetic intermediate of drugs. It can be involved in the synthesis of certain drugs such as atorvastatin and carbidoxan.
Preparation Method:
(2S)-2-(1H-tetrazol-1-yl) propionic acid can be synthesized by the following steps:
1. reacting chloroacetaldehyde with tetrazolium to generate tetrazolium acetaldehyde;
2. converting tetrazolium acetaldehyde into tetrazolium ethane by alkylation reaction;
3. reacting tetrazole ethane with (Boc)2O in the presence of carbon disulfide to obtain (N-Boc) tetrazole acetone;
4. Finally, (N-Boc) tetrazolacetone was treated with HCl to give the final product (2S)-2-(1H-tetrazol-1-yl) propionic acid.
Safety Information:
Safety information for (2S)-2-(1H-tetrazol-1-yl) propionic acid has not been fully collated and reported. However, like most organic compounds, it can cause irritation to the skin, eyes and respiratory tract. Appropriate protective equipment should be worn during operation to avoid direct contact and inhalation. At the same time, please follow the correct laboratory practice for handling and storage.
Nature:
(2S)-2-(1H-tetrazol-1-yl) propionic acid is a colorless crystalline solid, soluble in water and some organic solvents. It is a chiral compound possessing two stereoisomers:(2S)-form and (2R)-form.
Use:
(2S)-2-(1H-tetrazol-1-yl) propionic acid is commonly used in the field of pharmaceutical chemistry as a synthetic intermediate of drugs. It can be involved in the synthesis of certain drugs such as atorvastatin and carbidoxan.
Preparation Method:
(2S)-2-(1H-tetrazol-1-yl) propionic acid can be synthesized by the following steps:
1. reacting chloroacetaldehyde with tetrazolium to generate tetrazolium acetaldehyde;
2. converting tetrazolium acetaldehyde into tetrazolium ethane by alkylation reaction;
3. reacting tetrazole ethane with (Boc)2O in the presence of carbon disulfide to obtain (N-Boc) tetrazole acetone;
4. Finally, (N-Boc) tetrazolacetone was treated with HCl to give the final product (2S)-2-(1H-tetrazol-1-yl) propionic acid.
Safety Information:
Safety information for (2S)-2-(1H-tetrazol-1-yl) propionic acid has not been fully collated and reported. However, like most organic compounds, it can cause irritation to the skin, eyes and respiratory tract. Appropriate protective equipment should be worn during operation to avoid direct contact and inhalation. At the same time, please follow the correct laboratory practice for handling and storage.
Last Update：2024-04-09 21:11:58
